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Seattle-Denver Center of Innovation (COIN)


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COIN Investigators & Staff

COIN Investigators


Lucas Donovan, MD, MS
Title: Core Investigator
Staff Pulmonary, Critical Care, and Sleep Medicine Physician
Location: Seattle
University of Washington webpage
See Dr. Donovan's Dimensions profile that includes: publications, grants, datasets, patents and clinical trials
I aim to understand and address gaps in the delivery of effective care, primarily in the areas of sleep disorders and lung disease. To do so, I work to adapt, test, and implement health system interventions that improve the reach of evidence-based services.
The VA seeks to deliver high-quality and patient-centered care. It is incredibly rewarding to work in an organization that shares my values and work with our nation's Veterans.
Through ongoing trials among patients with obstructive sleep apnea and chronic obstructive pulmonary disease, I am to inform sustainable health system strategies that improve the delivery of care and patients' quality of life.

The following images visualize Dr. Donovan's work. The word cloud is drawn from publication titles. The research collaboration map shows research relationships (click the image to enlarge):

Dr. Donovan's publication titles indicate his primary work is care of Veterans
Word cloud from pub titles
Dr. Donovan's collaborations are primarily from the University of Colorado
Research collaboration map
The following research fields have been used to summarize Dr. Donovan's publications and grants. The categories are based on 86 publications and 4 grants.
Publications Grants
Clinical Research Lung
Lung Behavioral and Social Science
Sleep Research Clinical Research
Chronic Obstructive Pulmonary Disease Health Services
Health Services Sleep Research
Prevention Clinical Trials and Supportive Activities
Behavioral and Social Science Chronic Obstructive Pulmonary Disease
Mental Health Mental Health
Brain Disorders Nutrition

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Recent Publications




Duan KI, Donovan LM. Coverage Decisions for Positive Airway Pressure Therapy: Intended and Unintended Consequences. Ann Am Thorac Soc. 2023 Jan;20(1):28-29. doi: 10.1513/AnnalsATS.202211-912ED. PMID: 36584987
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Hoerster KD, Hunter-Merrill R, Nguyen T, Rise P, Barón AE, McDowell J, Donovan LM, Gleason E, Lane A, Plumley R, Schooler M, Schuttner L, Collins M, Au DH, Ma J. Effect of a Remotely Delivered Self-directed Behavioral Intervention on Body Weight and Physical Health Status Among Adults With Obesity: The D-ELITE Randomized Clinical Trial. JAMA. 2022 Dec 13;328(22):2230-2241. doi: 10.1001/jama.2022.21177.
PMID: 36511927.
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Spece LJ, Weppner WG, Weiner BJ, Collins M, Adamson R, Berger DB, Nelson KM, McDowell J, Epler E, Carvalho PG, Woo DM, Donovan LM, Feemster LC, Au DH, Au DH, Sayre G. Primary Care Provider Experience With Proactive E-Consults to Improve COPD Outcomes and Access to Specialty Care. Chronic Obstr Pulm Dis. 2022 Dec 5. doi: 10.15326/jcopdf.2022.0357. Epub ahead of print. PMID: 36472622.
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Donovan LM, Patel SR. Approaching sleep apnea management in the setting of uncertainty. Sleep. 2022 Sep 23:zsac234. doi: 10.1093/sleep/zsac234. Epub ahead of print. PMID: 36149838.
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Donovan LM, Patel SR. The Challenges of Estimating Causal Effects of CPAP Therapy from Observational Data. Am J Respir Crit Care Med. 2022 Aug 16. doi: 10.1164/rccm.202207-1413LE. Epub ahead of print. PMID: 35973224.
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Au DH, Chang JA, Davidson TA, Donovan LM, Goss CH, Feemster LC, Stapleton RD. Translating Individual Mentorship to Generalizable Action: Lessons Learned From J Randall Curtis. J Pain Symptom Manage. 2022 Jun;63(6):e641-e642. doi: 10.1016/j.jpainsymman.2022.03.014. PMID: 35595377.
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Donovan LM, Parsons EC, McCall CA, He K, Sharma R, Gamache J, Pannick AP, McDowell JA, Pai J, Epler E, Duan KI, Spece LJ, Feemster LC, Kapur VK, Au DH, Palen BN. Impact of mail-based continuous positive airway pressure initiation on treatment usage and effectiveness. Sleep Breath. 2022 Mar 26. doi: 10.1007/s11325-022-02608-z. Epub ahead of print. PMID: 35347655.
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Donovan LM, Au DH. Sleep Apnea, Obesity, and Readmissions: Real Risks or Residual Confounding? Ann Am Thorac Soc. 2022 Mar;19(3):361-362. doi: 10.1513/AnnalsATS.202111-1304ED. PMID: 35230227.

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Donovan LM. Rural residence and adherence to continuous positive airway pressure therapy: have we overcome a barrier? J Clin Sleep Med. 2022 Feb 3. doi: 10.5664/jcsm.9916. Epub ahead of print. PMID: 35105438.
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Mog AC, Liang PS, Donovan LM, Sayre GG, Shaukat A, May FP, Glorioso TJ, Jorgenson MA, Wood GB, Mueller C, Dominitz JA. Timely Colonoscopy After Positive Fecal Immunochemical Tests in the Veterans Health Administration: A Qualitative Assessment of Current Practice and Perceived Barriers. Clin Transl Gastroenterol. 2022 Jan 19. doi: 10.14309/ctg.0000000000000438. Epub ahead of print. PMID: 35060937.
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Keller TL, Wright J, Donovan LM, Spece LJ, Duan K, Sulayman N, Dominitz A, Curtis JR, Au DH, Feemster LC. Association of Patient and Primary Care Provider Factors with Outpatient COPD Care Quality. Chronic Obstr Pulm Dis. 2021 Dec 16. doi: 10.15326/jcopdf.2021.0232. Epub ahead of print. PMID: 34915603.

Donovan LM, Mog AC, Blanchard KN, Magid KH, Syed AS, Kelley LR, Spece LJ, Palen BN, Arfons LM, Kirsh S, Au DH, Sayre GG. Staff Experiences with a Team-based Approach to Sleep Medicine Referrals: A Qualitative Evaluation. Ann Am Thorac Soc. 2021 Nov 17. doi: 10.1513/AnnalsATS.202107-838OC. Epub ahead of print. PMID: 34788585.

Donovan LM, Kapur VK. Understanding Sleep Apnea Physiology: A Potential Path to Improving PAP Effectiveness. Am J Respir Crit Care Med. 2021 Aug 3. doi: 10.1164/rccm.202106-1474ED. Epub ahead of print. PMID: 34344285.

Donovan L, Parsons E, Epler E, McCall C, He K, Sharma R, Duan K, Spece L, Feemster L, Kapur V, Au D, Palen B. 677 Impact of Remote Continuous Positive Airway Pressure Set-up on Treatment Usage and Effectiveness. Sleep. 2021 May 3;44(Suppl2):A264–A265.

Konikkara J, Kabir A, David R, Donovan L, Palen B. 659 Optimizing Telehealth technology in Sleep Medicine at a VA Medical center during the COVID19 pandemic. Sleep. 2021 May; 44(2Suppl):A257–258.

Donovan LM, Mog AC, Blanchard KN, Magid KH, Syed AS, Kelley LR, Palen BN, Parsons EC, McCall CC, Thompson W, Charlton M, Spece LJ, Kirsh S, Au DH, Sayre GG. Patient experiences with telehealth in sleep medicine: a qualitative evaluation. J Clin Sleep Med. 2021 Mar 23. doi: 10.5664/jcsm.9266. Epub ahead of print. PMID: 33755010.

Hawkins EJ, Lott AM, Danner AN, Malte CA, Hagedorn HJ, Berger D, Donovan LM, Sayre GG, Mariano AJ, Saxon AJ. Primary Care and Mental Health Prescribers, Key Clinical Leaders, and Clinical Pharmacist Specialists' Perspectives on Opioids and Benzodiazepines. Pain Med. 2021 Mar 1:pnaa435. doi: 10.1093/pm/pnaa435. Epub ahead of print. PMID: 33661287.

Donovan LM, PalenBN, Fernandes LA, Whittington MD, Feser WJ, Blankenhorn R, Gunzburger E,Grunwald GK, Gamache J, Liao JM, Kirsh S, Au DH. The Referral Coordination Team: A Redesign of Specialty Care to Enhance Service Delivery and Value in Sleep Medicine. NEJM Catalyst Innovations in Care Delivery Vol. 2 No. 2 February 2021. DOI:



Donovan LM, Palen BN, Syed A, Blankenhorn R, Blanchard K, Feser WJ, Magid K, Gamache J, Spece LJ, Feemster LC, Fernandes L, Kirsh S, Au DH. Nurse-led triage of new sleep referrals is associated with lower risk of potentially contraindicated sleep testing: a retrospective cohort study. BMJ Qual Saf. 2020 Dec 22:bmjqs-2020-011817. doi: 10.1136/bmjqs-2020-011817. Epub ahead of print. PMID: 33443226.

Griffith MF, Chen HP, Bekelman DB, Feemster LC, Spece LJ, Donovan LM, Au DH, Carey EP. Comorbid Anxiety and Depression, Though Underdiagnosed, Are Not Associated with High Rates of Low-Value Care in Patients with COPD. Ann Am Thorac Soc. 2020 Dec 11. doi: 10.1513/AnnalsATS.201912-877OC. Epub ahead of print. PMID: 33306930.

Duan KI, Spece LJ, Wong ES, Feemster LC, Donovan LM, Griffith MF, Keller TL, Bryant AD, Au DH. Low-value Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease and the Association with Health Care Utilization and Costs. Ann Am Thorac Soc. 2020 Dec 8. doi: 10.1513/AnnalsATS.202009-1128OC. Epub ahead of print. PMID: 33290180.

Spece LJ, Epler EM, Duan K, Donovan LM, Griffith MF, LaBedz S, Thakur N, Wiener RS, Krishnan JA, Au DH, Feemster LC. Reassessment of Home Oxygen Prescription after Hospitalization for COPD: A Potential Target for De-implementation. Ann Am Thorac Soc. 2020 Oct 19. doi: 10.1513/AnnalsATS.202004-364OC. Epub ahead of print. PMID: 33075243.

Patel SR, Donovan LM. The COVID-19 Pandemic Presents an Opportunity to Reassess the Value of Polysomnography. Am J Respir Crit Care Med. 2020 Aug 1;202(3):309-310. doi: 10.1164/rccm.202005-1546ED. PMCID: PMC7397790. PMID: 32510968.

Spece LJ, Donovan LM, Griffith MF, Keller T, Feemster LC, Smith NL, Au DH. Initiating Low-Value Inhaled Corticosteroids in an Inception Cohort with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2020 May;17(5):589-595. doi: 10.1513/AnnalsATS.201911-854OC. PMID: 31899652.

Donovan LM, Kapur VK. Screening commercial drivers for sleep apnea: are profits and public safety aligned? Sleep. 2020 Apr 15;43(4):zsaa043. doi: 10.1093/sleep/zsaa043. PMID: 32221540.

Keller T, Spece LJ, Donovan LM, Udris E, Coggeshall SS, Griffith M, Bryant AD, Casaburi R, Cooper JA Jr, Criner GJ, Diaz PT, Fuhlbrigge AL, Gay SE, Kanner RE, Martinez FJ, Panos RJ, Shade D, Sternberg A, Stibolt T, Stoller JK, Tonascia J, Wise R, Yusen RD, Au DH, Feemster LC. Association of Guideline-Recommended COPD Inhaler Regimens With Mortality, Respiratory Exacerbations, and Quality of Life: A Secondary Analysis of the Long-Term Oxygen Treatment Trial. Chest. 2020 Aug;158(2):529-538. doi: 10.1016/j.chest.2020.02.073. Epub 2020 Apr 9. PMCID: PMC7417382. PMID: 32278779.

Donovan LM, Yu L, Bertisch SM, Buysse DJ, Rueschman M, Patel SR. Responsiveness of Patient-Reported Outcomes to Treatment Among Patients With Type 2 Diabetes Mellitus and OSA. Chest. 2020 Mar;157(3):665-672. doi: 10.1016/j.chest.2019.11.011. Epub 2019 Nov 27. PMCID: PMC7609963. PMID: 31785255.

Donovan LM, Fernandes LA, Williams KM, Parsons EC, O'Hearn DJ, He K, McCall CA, Johnson KA, Kennedy MW, Syed AS, Thompson WH, Spece LJ, Feemster LC, Kirsh S, Au DH, Palen BN. Agreement of sleep specialists with registered nurses' sleep study orders in supervised clinical practice. J Clin Sleep Med. 2020 Feb 15;16(2):279-283. doi: 10.5664/jcsm.8182. Epub 2020 Jan 13. PMCID: PMC7053017. PMID: 31992435.



Griffith MF, Feemster LC, Zeliadt SB, Donovan LM, Spece LJ, Udris EM, Au DH. Overuse and Misuse of Inhaled Corticosteroids Among Veterans with COPD: a Cross-sectional Study Evaluating Targets for De-implementation. J Gen Intern Med. 2020 Mar;35(3):679-686. doi: 10.1007/s11606-019-05461-1. Epub 2019 Nov 11. PMCID: PMC7080925. PMID: 31713043.

Donovan LM, Shah A, Chai-Coetzer CL, Barbé F, Ayas NT, Kapur VK. Redesigning Care for OSA. Chest. 2020 Apr;157(4):966-976. doi: 10.1016/j.chest.2019.10.002. Epub 2019 Oct 19. PMCID: PMC7118239. PMID: 31639334.

Triplette M, Donovan LM, Crothers K, Madtes DK, Au DH. Prediction of Lung Cancer Screening Eligibility Using Simplified Criteria. Ann Am Thorac Soc. 2019 Oct;16(10):1280-1285. doi: 10.1513/AnnalsATS.201903-239OC. PMID: 31298946.

Donovan LM, Coggeshall SS, Spece LJ, Griffith MF, Palen BN, Parsons EC, Todd-Stenberg JA, Glorioso TJ, Carey EP, Feemster LC, Zeliadt SB, Kirsh S, Au DH. Use of In-Laboratory Sleep Studies in the Veterans Health Administration and Community Care. Am J Respir Crit Care Med. 2019 Sep 15;200(6):779-782. doi: 10.1164/rccm.201902-0313LE. PMC7330508 PMID: 31206308.

Donovan LM, Malte CA, Spece LJ, Griffith MF, Feemster LC, Zeliadt SB, Au DH, Hawkins EJ. Center Predictors of Long-Term Benzodiazepine Use in Chronic Obstructive Pulmonary Disease and Post-traumatic Stress Disorder. Ann Am Thorac Soc. 2019 Sep;16(9):1151-1157. doi: 10.1513/AnnalsATS.201901-048OC. PMC6812159 PMID: 31113231.

Donovan LM, Bertisch SM, Patel SR. Defining Exposure and Nonexposure in Observational Studies of Sleep Apnea Treatment. JAMA Otolaryngol Head Neck Surg. 2019 Aug 8. doi: 10.1001/jamaoto.2019.1880. Online ahead of print. PMID: 31393547.

Kapur VK, Donovan LM. Taking Care of Persistent Sleepiness in Patients with Sleep Apnea. Am J Respir Crit Care Med. 2019 Jun 1;199(11):1310-1311. doi: 10.1164/rccm.201812-2291ED. PMC6543718 PMID: 30589565.

Griffith MF, Feemster LC, Donovan LM, Spece LJ, Krishnan JA, Lindenauer PK, McBurnie MA, Mularski RA, Au DH. Poor Metered-Dose Inhaler Technique Is Associated with Overuse of Inhaled Corticosteroids in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2019 Jun;16(6):765-768. doi: 10.1513/AnnalsATS.201812-889RL. PMC6543465 PMID: 30763114.

Kapur VK, Donovan LM. Why a Single Index to Measure Sleep Apnea Is Not Enough. J Clin Sleep Med. 2019 May 15;15(5):683-684. doi: 10.5664/jcsm.7746. PMC6510677 PMID: 31053224.

Billings ME, Krishnan V, Su G, Donovan LM, Patel SR, Hudgel DW, Ahasic AM, Wilson KC, Thomson CC. Clinical Practice Guideline Summary for Clinicians: The Role of Weight Management in the Treatment of Adult Obstructive Sleep Apnea. Ann Am Thorac Soc. 2019 Apr;16(4):405-408. doi: 10.1513/AnnalsATS.201810-708CME. PMID: 30742491.

Donovan LM, Feemster LC, Udris EM, Griffith MF, Spece LJ, Palen BN, He K, Parthasarathy S, Strohl KP, Kapur VK, Au DH. Poor Outcomes Among Patients With Chronic Obstructive Pulmonary Disease With Higher Risk for Undiagnosed Obstructive Sleep Apnea in the LOTT Cohort. J Clin Sleep Med. 2019 Jan 15;15(1):71-77. doi: 10.5664/jcsm.7574. PMC6329538 PMID: 30621828.

Parsons EC, Carter JC, Wrede JE, Donovan LM, Palen BN. Practical implementation of noninvasive ventilation in Amyotrophic Lateral Sclerosis: lessons learned from a clinical case series. Can J Respir Ther. 2019 Jan 9;55:13-15. doi: 10.29390/cjrt-2018-020. eCollection 2019. PMC6591783 PMID: 31297440.

Donovan LM, Malte CA, Spece LJ, Griffith MF, Feemster LC, Engelberg RA, Au DH, Hawkins EJ. Risks of Benzodiazepines in Chronic Obstructive Pulmonary Disease with Comorbid Posttraumatic Stress Disorder. Ann Am Thorac Soc. 2019 Jan;16(1):82-90. doi: 10.1513/AnnalsATS.201802-145OC. PMC6344455 PMID: 30309243.

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Grants & Funding


Pragmatic Trial to Enhance Quality Safety, and Patient Experience in COPD -- EQuiP COPD

Patient-Centered Outcomes Research Institute (PCORI) website

Pragmatic Obstructive Sleep Apnea Weight Loss Trial Assessing Effectiveness and Reach (POWER)

NIH website:

Redesigning Medical specialty Outpatient DELivery through virtual SLEEP care (REMODEL-SLEEP)

NIH website: